課程資訊
課程名稱
進階動物生物技術
Advanced Animal Biotechnology 
開課學期
103-1 
授課對象
生物資源暨農學院  生物科技研究所  
授課教師
宋麗英 
課號
Biot5007 
課程識別碼
642EU0100 
班次
 
學分
全/半年
半年 
必/選修
選修 
上課時間
星期三2,3,4(9:10~12:10) 
上課地點
生技所415 
備註
本課程以英語授課。上課地點:生技大樓R415
總人數上限:10人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1031Biot5007_2014 
課程簡介影片
 
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課程概述

The objectives of this course are 1) to provide graduate students with an overview of recent developments in animal biotechnology; 2) to improve graduate students' presentation skills. After extensive review and discussion of various biotechnologies, each student will be asked to give a presentation in the area other than their own research. I will meet with all students individually several times during their literature search, preparation of presentation outline and presentation practice. Lab demonstrations of basic embryology techniques will be included as well. Guest speakers will plan to invite for the lectures as necessary. 

課程目標
1. Introduction and overview of animal biotechnology
2. Folliculogenesis, oogenesis, embryogenesis
3. In vitro maturation/fertilization and embryo culture — state of the art
4. Embryo cryopreservation
5. Genetic micromanipulations of embryos
6. DNA identifications of transgenetic
7. Transgenic animals as organ donors (xenotransplantation)
8. Human Assisted Reproductive Technology (ART)
9. Sperm and embryo sexing
10. Somatic cell nuclear transfer- state of the art
11. Telomere, telomerase and gene reprogramming in age of cloned animal
12. X chromosome inactivation
13. Genetic imprinting
14. Functional genomics in humans and animals-state of the art
15. Introduction of embryonic stem cells
16. Introduction of adult stem cells
17. Therapeutic cloning— state of the art 
課程要求
 
預期每週課後學習時數
 
Office Hours
 
指定閱讀
 
參考書目
1. Developmental Biology, eighth edition, Scott F. Gibert, Sinauer Associates, Inc., USA
2. Reproduction in Farm Animals, seventh edition, E.S.E.Hafez and B. Hafez, Lippincott Williams and Wilkins
3. Pathways to pregnancy and parturition, second edition, P.L. Senger, Current Conceptions, Inc. USA
4. PubMed, www.pubmed.gov 
評量方式
(僅供參考)
   
課程進度
週次
日期
單元主題
第1週
9/17  Introduction and overview of animal biotechnology  
第2週
9/24  In vitro maturation/ fertilization and embryo culture - state of the art 
第3週
10/01  Oocyte and embryo cryopreservation 
第4週
10/08  Human IVF/ICSI/ART 
第5週
10/15  Preimplantation Genetic Diagnosis (PGD) 
第6週
10/22  Nuclear reprogramming by somatic cell nuclear transfer 
第7週
10/29  Toward human therapeutic cloning 
第8週
11/05  Epigenetic reprogramming in cloned embryos 
第9週
11/12  Epigenetic reprogramming in cloned embryos_II 
第10週
11/19  Telomere, telomerase and gene reprogramming in age cloned animal 
第11週
11/26  Embryonic stem cells  
第12週
12/03  Exam_Multichoice and essay questions 
第13週
12/10  Adult stem cells  
第14週
12/17  Nuclear reprogramming by induced pluripoent stem cells -I 
第15週
12/24  Nuclear reprogramming by induced pluripoent stem cells-II 
第16週
12/31  Student presentation –  
第17週
1/07  Final Exam –
Final report submission